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Below is a description of the GenoCon CAD Application. For the GenoCon2 Promoter Design Challenge, you should replace this with a report of your promoter design.
Name: RIKEN GenoCon
Affiliation: RIKEN The Institute of Physical and Chemical Research
Date: 2012-10-17
GenoConPromoterCAD is a DNA computer aided design (CAD) program which uses plant gene sequence and expression data to create synthetic promoters for tissue and time specific expression. The experimental test of such synthetic promoters will be to measure firefly Luciferase in Arabidopsis plant body. The program provides a graphical user interface (GUI), so anyone can design promoters using options in a series of select menus and push buttons. The program is written in JavaScript, on an open platform that allows for easy user customization.
The program provides several plugin functions for promoter designs MotifMaxExpress function, MotifMinExpress function, and MotifMaxCircadian function, as well as HighChart function for graph visualization of expression data. MotifMaxExpress function picks up the sequence motifs from the gene with maximum expression in a specific developmental condition. MotifMinExpress function picks up the motifs with minimum expression in a specific developmental condition. MotifMaxCircadian function picks up the motifs with maximum circadian amplitude. HighChart function provides graph visualization of expression data under experimental conditions (AtGenExpress) and time evolution of expression under circadian conditions (DIURNAL). Programmer participants can fork and add to these functions for the GenoCon2 Special Programming Challenge A.